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CHTN History and Timeline

2024

The CHTN was refunded for its eighth grant renewal.

2023

McCall, SJ, Lubensky IA, Moskaluk CA, Parwani A, Radin K, Ramirez NC, von Menchhofen ZG, Washington MK, LiVolsi VA. The Cooperative Human Tissue Network of the National Cancer Institute: Supporting cancer research for 35 years. Mol Cancer Ther. 2023 Oct 2;22(10):1144-1153. doi: 10.1158/1535-7163. PMID: 37523711

2019

During the seventh funding period of the CHTN, Duke University replaced the University of Alabama Birmingham.

2018

Grizzle W, Sexton K, McGarvey, D, von Menchhofen Z, LiVolsi, VA. Lessons Learned During Three Decades of Operations of Two Prospective Bioresources. Biopreserv Biobank. 2018. 16:6 483-492. PMID: 304578779; PMCID: PMC6308275.

2014

Auer H, Mobley JA, Ayers LW, Bowen J, Chuaqui RF, Johnson LA, Livolsi VA, Lubensky IA, McGarvey D, Monovich LC, Moskaluk CA, Rumpel CA, Sexton KC, Washington MK, Wiles KR, Grizzle WE, Ramirez NC: The effects of frozen tissue storage conditions on the integrity of RNA and protein. Biotech Histochem. 2014. 89:518-528. PMID: 24799092. PMC ID:PMC4213858

2014

The CHTN was refunded for its sixth grant renewal.

2008

A standards based ontological approach to information handling for use by organizations providing human tissue for research. Edgerton ME, Morrison C, LiVolsi VA, Moskaluk CA, Qualman SJ, Washington MK, Grizzle WE. Cancer Inform. 2008;6:127-37. Epub 2008 Apr 10. PMID: 19259407

2008

The CHTN was refunded for its fifth grant renewal.

2007

Children's Hospital in Columbus was officially renamed Nationwide Children's Hospital.

2007

The CHTN was awarded a year of supplemental funding.

2004

Establishing a tumour bank: banking, informatics and ethics. Qualman SJ, France M, Grizzle WE, LiVolsi VA, Moskaluk CA, Ramirez NC, Washington MK. Br J Cancer. 2004 Mar 22;90(6):1115-9. doi: 10.1038/sj.bjc.6601678.

2002

Jewell SD, Srinivasan M, McCart LM, Williams N, Grizzle WH, LiVolsi V, MacLennan G, and Sedmak DD. Analysis of the molecular quality of human tissues: an experience from the Cooperative Human Tissue Network. Am J Clin Pathol., 2002. 118(5): 733-741. PMID: 12428794.

2001

During the fourth funding period of the CHTN, the University of Virginia was added and Vanderbilt University Medical Center replaced Case Western.

1997

Merz JF, Sankar P, Taube SE, Livolsi VA , Use of Human Tissues in Research: Clarifying Clinician and Researcher Roles and Information Flows, Journal of Investigative Medicine(1997) 252-257.

1996

During the third funding period of the CHTN, NDRI was transferred to the University of Pennsylvania.

1991

During the second funding period of the CHTN, Case Western Reserve University and Children's Hospital in Columbus, OH were awarded as part of the grant renewal.

1987

Availability of human tissues for research in cancer. Clausen KP, Grizzle WE, LiVolsi VA, Newton WE. Science. 1987 Jul 3;237(4810):10-1. PMID: 3603008

1987

The CHTN was established by the NCI in response to the increased demand for high-quality biospecimens at an affordable cost for cancer research.

Original divisions: University of Alabama Birmingham, National Disease Research Interchange (University of Pennsylvania), and the Ohio State University