CHTN Data
Cumulative Data
Total # of Investigators Served Per Year (2012 - 2023)
Bar Graph Data
- 451 served in 2012.
- 441 served in 2013.
- 426 served in 2014.
- 409 served in 2015.
- 433 served in 2016.
- 424 served in 2017.
- 393 served in 2018.
- 373 served in 2019.
- 317 served in 2020.
- 342 served in 2021.
- 345 served in 2022.
- 343 served in 2023.
Total Samples Distributed by the CHTN
Bar Graph Data
- 1,599 distributed in 1987.
- 17,794 distributed in 1990.
- 42,053 distributed in 1992.
- 88,034 distributed in 1994.
- 150,056 distributed in 1996.
- 240,199 distributed in 1998.
- 362,291 distributed in 2000.
- 479,022 distributed in 2002.
- 590,236 distributed in 2004.
- 716,424 distributed in 2006.
- 820,129 distributed in 2008.
- 909,833 distributed in 2010.
- 1,010,122 distributed in 2012.
- 1,103,594 distributed in 2014.
- 1,152,612 distributed in 2015.
- 1,202,195 distributed in 2016.
- 1,246,402 distributed in 2017.
- 1,283,393 distributed in 2018.
- 1,318,939 distributed in 2019.
- 1,349,703 distributed in 2020.
- 1,385,041 distributed in 2021.
- 1,411,847 distributed in 2022.
- 1,452,957 distributed in 2023.
Samples Distributed Per Year (1987 - 2023)
Bar Graph Data
- 1,599 distributed in 1987.
- 5,229 distributed in 1988.
- 5,542 distributed in 1989.
- 5,424 distributed in 1990.
- 10,702 distributed in 1991.
- 13,557 distributed in 1992.
- 18,428 distributed in 1993.
- 27,553 distributed in 1994.
- 34,782 distributed in 1995.
- 27,240 distributed in 1996.
- 41,530 distributed in 1997.
- 48,613 distributed in 1998.
- 57,720 distributed in 1999.
- 64,372 distributed in 2000.
- 68,142 distributed in 2001.
- 48,589 distributed in 2002.
- 52,115 distributed in 2003.
- 59,099 distributed in 2004.
- 62,959 distributed in 2005.
- 63,229 distributed in 2006.
- 48,113 distributed in 2007.
- 55,592 distributed in 2008.
- 46,066 distributed in 2009.
- 43,638 distributed in 2010.
- 43,821 distributed in 2011.
- 56,468 distributed in 2012.
- 47,112 distributed in 2013.
- 46,360 distributed in 2014.
- 49,018 distributed in 2015.
- 49,583 distributed in 2016.
- 44,207 distributed in 2017.
- 36,991 distributed in 2018.
- 35,546 distributed in 2019.
- 30,764 distributed in 2020.
- 35,338 distributed in 2021.
- 32,220 distributed in 2022.
- 41,110 distributed in 2023.
2023 Annual Data
Top 5 Anatomic Sites collected in 2023 |
|---|
Kidney |
Colon |
Lung |
Breast |
Ovary |
# of Letters of Support provided in 2023 |
27 |
|---|---|
Total # of Investigators Served |
343 |
# of Samples Distributed |
41,110 |
# of TMA Slides Distributed |
311 |
Digital Images provided |
841 |
Top 5 High Impact publications for 2023 |
|---|
Lin, J. R., Wang, S., Coy, S., Chen, Y. A., Yapp, C., Tyler, M., ... & Sorger, P. K. (2023). Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer. Cell, 186(2), 363-381. |
Jayabal, P., Zhou, F., Ma, X., Bondra, K. M., Blackman, B., Weintraub, S. T., ... & Shiio, Y. (2023). Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma. Cell Reports, 42(2). |
Read KA, Jones DM, Pokhrel S, Hales EDS, Varkey A, Tuazon JA, Eisele CD, Abdouni O, Saadey A, Leonard MR, Warren RT, Powell MD, Boss JM, Hemann EA, Yount JS, Xin G, Ghoneim HE, Lio CJ, Freud AG,Collins PL, Oestreich KJ. Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity Nat Commun. 2023 Mar 24;14(1):1652. |
Dhillon, P., Mulholland, K. A., Hu, H., Park, J., Sheng, X., Abedini, A., ... & Susztak, K. (2023). Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development. Nature Communications, 14(1), 559. |
Thacker, G., Henry, S., Nandi, A., Debnath, R., Singh, S., Nayak, A., ... & Chakrabarti, R. (2023). Immature natural killer cells promote progression of triple-negative breast cancer. Science translational medicine, 15(686), eabl4414. |
2022 Annual Data
Top 5 Anatomic Sites collected in 2022 |
|---|
Kidney |
Blood |
Breast |
Colon |
Lung |
# of Letters of Support provided in 2022 |
43 |
|---|---|
Total # of Investigators Served |
345 |
# of Samples Distributed |
32,220 |
# of TMA Slides Distributed |
248 |
Digital Images provided |
4,010 |
Top 5 High Impact publications for 2022 |
|---|
Murrow, L. M., Weber, R. J., Caruso, J. A., McGinnis, C. S., Phong, K., Gascard, P., ... & Gartner, Z. J. (2022). Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution. Cell Systems, 13(8), 644-664. |
Zhou, W., Zhou, L., Zhou, J., Chu, C., Zhang, C., Sockolow, R. E., ... & Sonnenberg, G. F. (2022). ZBTB46 defines and regulates ILC3s that protect the intestine. Nature, 609(7925), 159-165. |
Feng, Z., He, X., Zhang, X., Wu, Y., Xing, B., Knowles, A., ... & Hua, X. (2022). Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues. Nature Cancer, 3(5), 581-594. |
Liu, H., Doke, T., Guo, D., Sheng, X., Ma, Z., Park, J., ... & Susztak, K. (2022). Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease. Nature Genetics, 54(7), 950-962. |
Sun, S., Brazhnik, K., Lee, M., Maslov, A. Y., Zhang, Y., Huang, Z., ... & Montagna, C. (2022). Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers. The Journal of Clinical Investigation, 132(5). |
2021 Annual Data
Top 5 Anatomic Sites collected in 2021 |
|---|
Blood |
Kidney |
Lung |
Breast |
Colon |
# of Letters of Support provided in 2021 |
32 |
|---|---|
Total # of Investigators Served |
342 |
# of Samples Distributed |
35,338 |
# of TMA Slides Distributed |
275 |
Digital Images provided |
2,386 |
Top 5 High Impact publications for 2021 |
|---|
Miao Z, Balzer MS, Ma Z, et al. Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets. Nat Commun. 2021;12(1):2277. Published 2021 Apr 15. doi:10.1038/s41467-021-22266-1 |
Frank AC, Ebersberger S, Fink AF, et al. Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype. Nat Commun. 2019;10(1):1135. Published 2019 Mar 8. doi:10.1038/s41467-019-08989-2 |
Saxena V, Gao H, Arregui S, et al. Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli. Nat Commun. 2021;12(1):2405. Published 2021 Apr 23. doi:10.1038/s41467-021-22672-5 |
You D, Hillerman S, Locke G, et al. Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor. J Immunother Cancer. 2021;9(1):e001402. doi:10.1136/jitc-2020-001402 |
Northcott PA, Buchhalter I, Morrissy AS, et al. The whole-genome landscape of medulloblastoma subtypes. Nature. 2017;547(7663):311-317. doi:10.1038/nature22973 |